Methylergometrine EP Impurity I Acetate CAS 724767-21-9 (free base)
| CAS No. | 724767-21-9 (free base) |
| Molecular Formula | 2*C20H25N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H25N3O2CH2O2, Methylergometrine EP Impurity I Acetate contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 385.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Methylergometrine EP Impurity I Acetate (CAS 724767-21-9 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25N3O2CH2O2 and a molecular weight of 385.46 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Methylergometrine EP Impurity I Acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C20H25N3O2 CH2O2 |
| Molecular Weight | 385.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Methylergometrine Standards
- Methylergometrine (CAS 113-42-8)
- Methylergometrine EP Impurity C (CAS 478-94-4)
- Methylergometrine Impurity 1 (CAS 5516-91-6)
- Methylergometrine Impurity 13 (CAS 569-26-6)
- Methylergometrine EP Impurity G (CAS 5793-04-4)
- Methylergometrine Impurity 6 (CAS CATO-C4X-19486)
- Methylergometrine Impurity 7 (CAS CATO-C4X-19487)
Recommended Standards
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- Acalabrutinib Impurity 27 (CAS CATO-C4X-305527)
- Manganese benzoate (CAS 636-13-5)
- Binimetinib (CAS 606143-89-9)
- Benzyl (R)-2-(Boc-amino)-5-(dimethylamino)-5-oxopentanoate (CAS 721927-49-7)
- Ethyl 2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)acetate (CAS 338962-53-1)
- Ethyl 2-(5-amino-1H-indol-1-yl)acetate (CAS 528884-67-5)
- tert-Butyl (2-amino-3,3,3-trifluoropropyl)carbamate (CAS 1279818-32-4)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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